Psoriasis Keys Are Found in Your DNA

About two to three percent of the national population develops psoriatic disease, although scientists believe that at least 10 percent of the population inherit one or more genes that lead to the disease. 

Genes Cause Eventual Psoriasis Diagnosis

Research on this began in the 70s but recently, because of scientific advances in genetic technology and increased funding, has lead to greater information. According to, The BioBank is slated to be the world’s largest collection of psoriasis-related DNA in the world available to qualified researchers. Scientists and researchers have identified around 25 genetic variants that make a person more likely to develop psoriatic disease. They have also identified several areas in the human genome where multiple genes may be involved in psoriasis and psoriatic arthritis

Psoriasis Triggers

Triggers tend to be unique per person. What triggers one person’s psoriasis, is fine for the next. Possible triggers include the following:

  • Stress – this can cause the first flare or aggravate existing psoriasis.
  • Injury to Skin – the Koebner phenomenon happens when psoriasis appears in areas of the skin that have been injured or traumatized (i.e sunburn, vaccinations, scratches.)
  • Medication – associated with flares are Lithium, Antimalarials, Inderal, Quinidine, and Indomethacin.
  • Infection – anything that can affect your immune system can affect psoriasis, in particular, strep throat.
  • Unproven – some people link flares to their diet, allergies, and weather.

Psoriatic Arthritis

Psoriatic arthritis affects up to 30 percent of those with psoriasis. It usually affects the distal joints and can cause swelling, stiffness, pain in and around the joints, nail changes, and overall fatigue.

Early recognition, diagnosis, and treatment are critical to relieving pain and inflammation as well as help prevent joint damage. Studies show delaying treatment by as few as six months can result in permanent joint damage.

To learn much more about psoriatic arthritis go to

To learn more about our DNA testing services, contact Test Smartly Labs of Kansas City today.

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